Table 2.

Effects of MMDA and Group on systolic pressure and subjective effects.

	SOL (N=10)						RAP (N=11)						OPP (N=12)
	placebo		low MDMA		high MDMA		placebo		low MDMA		high MDMA		placebo		low MDMA		high MDMA
Systolic Pressure	−3.0	(1.1)	1.7	(1.1) *	7.8	(1.5) *§	−2.5	(1.0)	1.7	(1.2) *	8.0	(1.4) *§	1.9	(1.1)	2.4	(1.1)	14.7	(1.5) *§
DEQ
Like Drug	14.2	(2.3)	21.5	(2.6)	46.9	(3.8) *§	22.9	(2.9)	29.3	(3.7)	42.9	(3.6) *§	17.3	(2.6)	28.4	(3.3) *	49.4	(3.9) *§
Dislike Drug	13.0	(2.1)	18.9	(2.3)	12.6	(2.2)	10.2	(1.9)	9.2	(2.1)	17.2	(2.8) *§	8.1	(1.5)	18.6	(3.1) *	12.1	(1.8)
Want More	12.5	(2.5)	16.6	(2.5)	43.2	(4.6) *§	17.8	(3.1)	22.8	(3.4)	32.1	(4.0) *§	14.9	(2.4)	27.5	(3.6) *	32.7	(3.7) *
VAS
Anxious	−2.1	(1.0)	0.6	(2.1)	−3.5	(2.0)	−7.4	(2.3)	−3.3	(1.7)	5.5	(2.6) *§	−7.7	(1.6)	−2.4	(1.7)	0.8	(1.9) *
Elated	4.9	(1.6)	1.0	(1.4)	13.6	(2.8)	−1.2	(2.3)	4.4	(1.6)	19.3	(2.9)	1.4	(1.9)	5.8	(1.7)	19.0	(2.8)
Insightful	2.9	(2.0)	1.8	(1.7)	15.8	(2.9) *§	3.8	(1.9)	7.5	(1.7)	13.4	(1.9) *	1.4	(2.5)	10.3	(1.9) *	13.7	(2.9) *
Loving	1.1	(1.2)	0.6	(1.1)	2.7	(1.8)	−0.4	(0.5)	−2.4	(1.4)	3.7	(1.6) §	−8.2	(2.2)	−7.7	(2.1)	−0.4	(1.2) *
Restless	−0.9	(2.0)	12.6	(2.2) *	6.6	(3.4)	1.6	(2.2)	4.6	(2.3)	17.5	(3.4) *§	4.3	(2.0)	2.2	(2.7)	12.4	(2.9) *§
Sedated	0.8	(1.8)	4.0	(2.3)	2.1	(2.5)	7.3	(2.2)	−2.5	(3.4) *	2.4	(2.2)	−4.4	(2.4)	7.1	(2.6) *	−2.7	(3.0) §
Stimulated	−1.0	(0.9)	6.8	(1.6) *	17.4	(2.8) *§	−1.5	(2.3)	4.8	(1.9)	24.5	(3.5) *§	−10.2	(2.8)	5.2	(1.9) *	22.0	(3.8) *§

An * denotes significantly different than placebo (p < 0.05).

An § denotes high MDMA significantly different than low MDMA (p < 0.05).