Table 3.
ECD According to Donor Diabetes History
| Baseline Model (N=1090)
| |||||
|---|---|---|---|---|---|
| Donor Diabetes History | P-value* | ||||
| No | Yes | ||||
|
| |||||
| N | Baseline ECD median (quartiles) | N | Baseline ECD median (quartiles) | ||
| Overall | 891 | 2671 (2462, 2874) | 199 | 2618 (2445, 2864) | |
| Recipient Diabetes History‡ | 0.69 | ||||
| No | 736 | 2670 (2448, 2874) | 163 | 2618 (2444, 2834) | |
| Yes | 113 | 2652 (2500, 2862) | 28 | 2670 (2508, 2873) | |
| Recipient Diagnosis‡ | 0.10 | ||||
| Fuchs’ | 552 | 2668 (2442, 2873) | 124 | 2655 (2490, 2846) | |
| PACE | 298 | 2668 (2496, 2857) | 71 | 2594 (2426, 2816) | |
| Recipient Age | 0.86 | ||||
| <60 years | 135 | 2670 (2487, 2894) | 27 | 2695 (2397, 2959) | |
| 60–<70 years | 235 | 2646 (2428, 2842) | 49 | 2577 (2445, 2794) | |
| ≥70 years | 521 | 2686 (2475, 2879) | 123 | 2637 (2487, 2881) | |
| Donor Age | 0.18 | ||||
| <50 years | 218 | 2767 (2543, 2971) | 18 | 2721 (2483, 2902) | |
| 50 – <66 years | 376 | 2658 (2443, 2870) | 95 | 2603 (2439, 2829) | |
| ≥66 years | 297 | 2625 (2448, 2824) | 86 | 2621 (2445, 2866) | |
| Donor Race | 0.05 | ||||
| White | 840 | 2668 (2459, 2874) | 184 | 2627 (2472, 2861) | |
| Non-White | 51 | 2679 (2551, 2878) | 15 | 2550 (2166, 2959) | |
| 10-Year Model (N=176)
| |||||
|---|---|---|---|---|---|
| Donor Diabetes History | P-value† | ||||
| No | Yes | ||||
|
| |||||
| N | 10-Year ECD median (quartiles) | N | 10-Year ECD median (quartiles) | ||
| Overall | 149 | 622 (502, 764) | 27 | 570 (493, 774) | |
| Recipient Diabetes History | NA | ||||
| No | 134 | 616 (506, 762) | 24 | 562 (493, 703) | |
| Yes | 15 | 646 (454, 869) | 3 | NA | |
| Recipient Diagnosis§ | NA | ||||
| Fuchs’ | 125 | 613 (500, 758) | 20 | 534 (483, 609) | |
| PACE | 21 | 675 (589, 1094) | 6 | NA | |
| Recipient Age | NA | ||||
| <60 years | 46 | 675 (530, 846) | 5 | NA | |
| 60–<70 years | 48 | 623 (486, 912) | 7 | NA | |
| ≥70 years | 55 | 613 (493, 730) | 15 | 570 (493, 860) | |
| Donor Age | NA | ||||
| <50 years | 51 | 688 (565, 942) | 4 | NA | |
| 50 – <66 years | 59 | 606 (461, 760) | 11 | 600 (472, 850) | |
| ≥66 years | 39 | 590 (480, 698) | 12 | 513 (488, 562) | |
| Donor Race | NA | ||||
| White | 144 | 623 (504, 771) | 25 | 570 (502, 774) | |
| Non-White | 5 | NA | 2 | NA | |
|
| |||||
| Longitudinal Model (N=2344 images from 591 subjects) | P-value* | ||||
|
| |||||
| Recipient Diabetes History‡ | NA | 0.69 | |||
| Recipient Diagnosis‡ | 0.43 | ||||
| Recipient Age | 0.90 | ||||
| Donor Age | 0.09 | ||||
| Donor Race | 0.91 | ||||
*
Test for effect modification with donor diabetes and the indicated factor. Continuous factors were used for donor age and recipient age.
†
Too few cases at 10 years for subgroup analyses.
‡
There were 50 patients with unknown diabetes history and 45 patients with “other” diagnoses at baseline.
§
There were 4 patients with “other” diagnoses at 10 years.