Table 2.
Characteristics of patients with various subtypes of B-ALL and the relationship with different prognostic factors, and expression of CD95 and other markers
| Variables |
ProB-All
Mean (SD) or Frequency |
Early preB-All
Mean (SD) or Frequency |
PreB-All
Mean (SD) or Frequency |
P. value |
|---|---|---|---|---|
| Patients | 5 (8.6%) | 29 (50%) | 24 (41.4%) | - |
| Age (years) | 5.10 (3.51) | 5.03 (2.92) | 4.60 (3.69) | 0.8 |
| WBC×10 9 /L | 42.74 (87.92) | 13.85 (14.98) | 30.65 (28.66) | 0.068 |
| Platelet×10 9 /L | 156.80 (122.9) | 109.69 (126.16) | 62.04 (70.36) | 0.1 |
| CRD (days) | 745 (27) | 638 (51) | 634 (58) | 0.6 |
| Survival (days) | 787.6 (59.4) | 672 (45) | 725 (33) | 0.5 |
| CR time (days) | 14.00 (0.00) | 18.93 (8.9) | 20.63 (7.13) | 0.3 |
| % blast (PB) | 85.0 (0.00) | 45.00 (28.80 | 54.24 (22.05) | 0.4 |
| % blast (BM) | 68.82 (28.46) | 80.19 (20.67) | 69.37 (22.21) | 0.1 |
| Patients with EMI | 1 (3.3%) | 13 (41.9%) | 17 (54.8%) | 0.049 |
| TEL/AML1 positive | 1 (14.2%) | 3 (42.9%) | 3 (42.9%) | 0.9 |
| Death rate | 1 (12.5%) | 6 (75%) | 1 (12.5%) | 0.2 |
| CR rate | 5 (9.3%) | 28 (51.9%) | 21 (38.8%) | 0.6 |
| CD20 expression (%) | 11.3 (11.3) | 9.3 (4.9) | 50.18 (20.81) | - |
| CD44 expression (%) | 34.21 (23.67) | 23.10 (22.86) | 25.48 (16.21) | 0.5 |
| CD34 expression (%) | 54.56 (31.82) | 29.90 (30.47) | 37.82 (31.9) | 0.2 |
| CD95 expression (%) | 21.28 (23.45) | 11.89 (11.99) | 15.03 (17.41) | 0.4 |
Data represent mean ± SD (standard deviation) according to number (%) and mean±standard error for durations. FAB: French-American-British classification of ALL; PB: peripheral blood; BM: bone marrow; WBC: white blood cell; EMI: extramedullary involvement; CR: complete remission; CRD: complete remission duration