Table 7. Genes differentially expressed (FDR-adjusted P-Value < 0.005 and log2(fold change) > |1.3|) between myostatin-reduced and wild-type mice in the skeletal muscle.
Gene* | Log2 (Myostatin-reduced/Wild-type) | FDR-adjusted P-value |
---|---|---|
ERCC2 | 4.19 | 2.5E-03 |
DGCR8 | 4.09 | 2.5E-03 |
METTL21E | 3.48 | 2.5E-03 |
GSPT1 | 2.38 | 2.5E-03 |
ACTC1 | 2.29 | 2.5E-03 |
GREM2 | 1.91 | 2.5E-03 |
SLN | 1.89 | 2.5E-03 |
CDH4 | 1.88 | 2.5E-03 |
F830016B08RIK | 1.87 | 2.5E-03 |
KATNAL2 | 1.74 | 2.5E-03 |
IL12A | 1.47 | 2.5E-03 |
MYBPH | 1.34 | 2.5E-03 |
VASH2 | 1.30 | 2.5E-03 |
*Expanded gene names, listed in alphabetical order: ACTC1 = actin, alpha, cardiac muscle 1; CDH4 = cadherin 4, type 1, R-cadherin; DGCR8 = DGCR8 microprocessor complex subunit; ERCC2 = Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 2; F830016B08RIK = RIKEN cDNA F830016B08 gene; GREM2 = gremlin 2, DAN family BMP antagonist; GSPT1 = G1 to S phase transition 1; IL12A = interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35); KATNAL2 = katanin p60 subunit A-like 2; METTL21E = methyltransferase like 21E; MYBPH = myosin binding protein H; SLN = sarcolipin; VASH2 = vasohibin 2