Table 3. Non-Fibrotic Bronchi: Major Changes in Gene Expression.
| Gene | Gene Description | Fold-Increase a |
|---|---|---|
| Cldn18 | Claudin 18 | 9.4 |
| Gas6 | Growth arrest specific 6 | 9.2 |
| Nog | noggin | 8.0 |
| Lrp10 | Low-density lipoprotein receptor-related protein 10 | 5.6 |
| Nrg1 | neuregulin 1 | 5.3 |
| Tubb4 | Tubulin, beta 4 | 4.9 |
| Apln | Apelin | 4.7 |
| Slc15a1 | solute carrier family 15 (oligopeptide transporter), member 1 | 4.7 |
| Arhgap17 | Rho GTPase activating protein 17 | 3.9 |
| Clic5 | Chloride intracellular channel 5 | 3.9 |
| Akap5 | A kinase (PRKA) anchor protein 5 | 3.9 |
| Zfp318 | Zinc finger protein 318 | 3.8 |
| Hdac10 | Histone deacetylase 10 | 3.7 |
| Ubr2 | Ubiquitin protein ligase E3 component n-recognin 2 | 3.6 |
| Pdgfrb | Platelet derived growth factor receptor, beta polypeptide | 3.5 |
| Fold-Decrease a | ||
| S1pr1 | sphingosine-1-phosphate receptor 1 | -5.2 |
| Tlr2 | Toll-like receptor 2 | -5.3 |
| Rasgrp1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | -5.4 |
| Stra6 | Stimulated by retinoic acid gene 6 | -5.5 |
| C9 | complement component 9 | -5.8 |
| Sbp | spermine binding protein | -6.2 |
| Lgi1 | Leucine-rich, glioma inactivated 1 | -6.3 |
| Sorl1 | Sortilin-related receptor, LDLR class A repeats-containing | -6.4 |
| Spr | sepiapterin reductase | -6.6 |
| Slc23a1 | solute carrier family 23 (nucleobase transporters), member 1 | -6.9 |
| Zfp853 | Zinc finger protein 853 | -7.5 |
| Ppara | peroxisome proliferator activated receptor alpha | -7.7 |
| Cyp2a3 | cytochrome P450, family 2, subfamily a, polypeptide 3 | -8.5 |
| Dmrt2 | Doublesex and mab-3 related transcription factor 2 | -9.0 |
| Gad1 | glutamate decarboxylase 1 | -10.1 |
aFold change relative to air-exposed controls