Table 2.

Demographic and clinical characteristics of Cowden syndrome and Cowden syndrome-like patients with endometrial cancer (n=371).

Variable		N (%)
Age	Mean Median Range <30 years 30–50 years >50 years	53 years 54 years (21–88) 16 (5%) 110 (33%) 204 (62%)
Histology	Endometrioid Serous/clear cell Mucinous Sarcoma NOS*/Unknown	156 (42%) 19 (5%) 1 (0.3%) 10 (2.7%) 185 (50%)
Race	White African American Asian Others Unknown	218 (59%) 9 (2.4%) 8 (2.2%) 21 (5.7%) 115 (31%)
Uterine fibroid	Yes No	139 (37.5%) 232 (62.5%)
Breast Cancer	Yes No	226 (61%) 145 (39%)
Renal cancer	Yes No	18 (5%) 352 (95%)
Thyroid cancer	Yes No	51 (13.7%) 320 (86.3%)
Macrocephaly	Yes No	84 (22.6%) 287 (77.4%)
Cleveland Clinic Score	Mean	9.3 (1–69)
PTEN protein level	1 2 3 4	69 (27.7%) 59 (23.7%) 60 (24.1%) 61 (24.5%)

^*Not otherwise specified