Table 2. STM mutants with decreased competitive index in fleas.

STM mutant	Y. pestis KIM10+ locus tag	Gene	Tn5 insertion site*	Product	Competitive index†
In vivo	In vitro
3C1	y2631	galU	2 895 235	UTP-glucose 1-phosphate uridylyltransferase	0.0037	5.23
3D9	y2283		2 519 947	Hypothetical	0.0383	2.07
5F7	y1748		1 929 492	Putative transposase	0.0024	1.67
9F7	y2422		2 689 958	Hypothetical	0.0306	1.20
9H9	y1917	arnB	2 110 322	UDP-4-amino-4-deoxy-l-arabinose-oxoglutarate aminotransferase	0.0222	1.10
10A3	y3386		3 734 381	Carbohydrate symporter permease	0.0259	1.32
17B4	y4035‡		4 474 082‡	Hypothetical	0.0331	3.28

^*Base pair location of transposon insertion site according to KIM10+ genome.

^†Competitive index of STM mutant to KIM6+ at 4 days post-infection/inoculation.

^‡Transposon inserted into promoter region.