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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: Semin Cell Dev Biol. 2014 Sep 26;0:35–43. doi: 10.1016/j.semcdb.2014.09.015

Fig. 1. Dynamics and disorder among human signaling proteins.

Fig. 1

Interior protein color indicates the level of structural disorder calculated using the meta approach [75]. A yellow halo indicates that the dynamics of the protein have been characterized in live cells. *The dynamics of SMAC, CASP3, CASP8, and CDK2 were characterized by enzymatic activity rather than protein expression levels. Protein-protein interactions were obtained from the Biomolecular Interaction Network Database [76].