Table 1. Distributions of examined variables by case-control status.

Variable	Controls (n=212)	Barrett's Esophagus (n=173)
Demographic Variables
Age (years; mean (SD))	47.25 (11.88)	56.49 (11.35)
Body mass index (kg/m2; mean (SD))	28.37 (4.51)	28.41 (4.08)
Race (%)
White	70.9	81.6
Non-white/unknown	29.1	19.4
Ever-Smoked (%)	31.5	48.0
Pack-years smoked	9.8 (2.2, 21.0)	22.0 (9.0, 47.0)
Frequency of Alcohol Use (%)
Never/Less than monthly	15.7	16.1
Monthly	21.3	16.7
Weekly	47.7	44.4
Daily	15.2	22.8
GERD Score (out of 13)	6 (4, 8)	6 (4, 8)
GERD Score without Heartburn and Regurgitation (out of 7)	2 (2, 3)	2 (1, 3)
Ever Experienced Daily Heartburn (%)
Never	10.3	11.0
Monthly	22.1	20.8
Weekly	29.1	28.9
Daily	38.5	39.3
Ever Experienced Daily Regurgitation (%)
Never	10.3	13.3
Monthly	36.2	25.4
Weekly	32.4	36.4
Daily	21.1	24.9
Hormone Variables
DHEA (nmol/L)	9.19 (5.90, 11.84)	6.33 (3.66, 9.25)
DHEAS (umol/L)	3.32 (2.25, 4.72)	2.38 (1.23, 3.93)
Androstenediol (pmol/L)	2323.6 (1715.3, 3162.9)	2004.2 (1508.8, 2877.4)
Androstenedione (nmol/L)	2.83 (2.31, 3.87)	2.69 (2.2, 3.4)
Testosterone (nmol/L)	14.1 (10.7, 18.3)	14.2 (11.2, 18.3)
DHT (pmol/L)	1107.0 (767.4, 1559.0)	1130.3 (768.7, 1442.6)
3adiol3g (nmol/L)	3.33 (2.41, 4.95)	3.36 (2.28, 4.82)
3adiol17g (nmol/L)	8.66 (6.00, 12.36)	8.87 (5.38, 11.87)
ADT (pmol/L)	803.6 (617.1, 1031.6)	656.1 (490.3, 885.3)
ADT-G (nmol/L)	78.0 (56.4, 119.0)	69.8 (45.4, 108.2)
E1 (pmol/L)	128.0 (97.5, 161.6)	123.4 (97.0, 146.0)
E1S (nmol/L)	1.58 (1.04, 2.33)	1.39 (0.82, 2.04)
E2 (pmol/L)	90.4 (73.3, 112.7)	90.7 (73.4, 107.5)
SHBG (nmol/L)	31.5 (19.2, 44.5)	30.8 (22.3, 43.6)
Free Testosterone (nmol/L)	0.29 (0.24, 0.38)	0.29 (0.24, 0.37)
Free DHT (pmol/L)	27.13 (21.21, 35.44)	27.41 (20.91, 37.09)
Free Estradiol (pmol/L)	2.42 (1.93, 3.08)	2.32 (1.87, 2.94)

Unless otherwise stated, statistics shown are the median and interquartile range.