Fig. 3.

LY294002 inhibits LY uptake in human macrophages. LY uptake was determined in THP-1 macrophages (a) or HMDM (b) in response to 24 h incubation with DMSO vehicle control or the indicated concentration of LY294002. Data represent means ± SD from three independent experiments, the uptake in vehicle treated cells has been arbitrarily assigned as 100 %. Statistical analysis was performed using one-way ANOVA with Games-Howell (a) or Tukey’s (b) post hoc analysis, ***P < 0.001, **P < 0.01