Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
CEPN blocks ACh-evoked Ca2+ influx. Representative result of 4 experiments in the presence of nifedipine. Under Ca2+-free conditions (0 Ca2+ + 0.5 mM EGTA), ACh induced a fast transient contraction. Following the addition of 2 mM Ca2+, a strong sustained contraction occurred, which was entirely reversed by CEPN. These experiments indicate that CEPN inhibits the nifedipine-resistant Ca2+ influx activated by ACh.
