Figure 8.

Analysis of motor coordination and balance. (a) Rotarod results of motor coordination and balance test after the preventive and therapeutic treatment showing improved effect of EB101 and Aβ ₄₂ + CFA/IFA-vaccine compared to other treated mice groups (P < 0.05) and (P < 0.02) versus control mice. Latency to fall on the rotarod apparatus was significantly improved in EB101 immunized mice. Values represent means of all six trials of a group/day. (b) Spatial learning and memory tested by fear conditioning-active avoidance test. The mean response time of each treatment group to reach the platform is represented. EB101 and Aβ ₄₂ + CFA/IFA immunized mice had significantly lower latencies than the other treatment groups (P < 0.01) versus control mice.