Table 3. Findings of other studies investigating the association of CRC susceptibility SNPs with prognosis.
Study | Cohort size | Outcomes assessed | SNPs investigated | ||||||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
rs10318 | rs10411210 | rs10505477 | rs10749971 | rs10795668 | rs10808555 | rs10936599 | rs11169552 | rs11213809 | rs11986063 | rs12953717 | rs1321311 | rs13254738 | rs1447295 | rs16892766 | rs16901979 | rs1862748 | rs1957636 | rs355527 | rs3802842 | rs3824999 | rs4444235 | rs4464148 | rs4779584 | rs4813802 | rs4925386 | rs4939827 | rs5934683 | rs6687758 | rs6691170 | rs6983267 | rs6983626 | rs7013278 | rs7014346 | rs70195668 | rs7136702 | rs719725 | rs7259371 | rs7837328 | rs961253 | rs9929218 | |||
Abuli[17] | 1,235 | OS | x | + | x | x | x | x | x | x | + | ||||||||||||||||||||||||||||||||
Cicek[23]γ | 460 | OS, DFS | x | x | x | x | |||||||||||||||||||||||||||||||||||||
Dai[18]γ | 285 | OS, R | - | x | - | x | x | x | x | x | x | x | x | + | x | x | - | x | - | x | x | x | x | + | x | ||||||||||||||||||
Garcia-Albeniz[24]§ | 1,509 | OS | - | ||||||||||||||||||||||||||||||||||||||||
Hoskins[19] | 583 | OS | x | x | x | x | x | x | x | x | x | x | x | ||||||||||||||||||||||||||||||
Passarelli[32] | 727 | CSS | x | x | |||||||||||||||||||||||||||||||||||||||
Phipps[20]§ | 2,611 | OS, CSS | x | x | x | x | x | x | x | x | x | - | x | x | x | x | x | x | |||||||||||||||||||||||||
Tenesa[21] | 2,838 | CSS | x | x | x | x | x | x | x | x | x | x | |||||||||||||||||||||||||||||||
Xing[22] | 380 | OS, DFS | x | x | x | x | x | x |
Key: + significantly increased survival,—significantly decreased survival, X no survival difference observed
OS—Overall survival, DFS—Disease free survival, CSS—cancer specific survival, R—recurrence
§—Based on overlapping cohort of patients
γ- Based on patients with stage II/III cancers.