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The ROC curves for predicting highly related interfaces using three methods, PCalign, Ialign, and I2I-SiteEngine. As shown by the red and magenta curves, our method PCalign gives an AUC value of 0.970, and for the backbone set 0.955. In comparison, Ialign gives an AUC of 0.980. I2I-SiteEngine performs slightly worse, with those predicted by match score, total score and t-score having AUC values of 0.831, 0.884 and 0.909 respectively.
