Table 1.
Characteristics of cases and controls. International Head and Neck Cancer Epidemiology Consortium
| Characteristics | Women, n (%) |
Men, n (%) |
|||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cases |
Controls |
Cases |
Controls |
||||||||||||||
| ≤45yo |
>45yo |
≤45yo |
>45yo |
≤45yo |
>45yo |
≤45yo |
>45yo |
||||||||||
| N | % | N | % | N | % | N | % | N | % | N | % | N | % | N | % | ||
| Cancer subsite | |||||||||||||||||
| Oral cavity | |||||||||||||||||
| Oral tongue | 81 | 16.0 | 362 | 10.3 | – | – | – | 166 | 11.0 | 781 | 5.9 | – | – | – | – | ||
| Floor of mouth | 23 | 4.6 | 301 | 8.5 | – | – | – | 157 | 10.4 | 1076 | 8.2 | – | – | – | – | ||
| Other parts, | 111 | 21.0 | 844 | 23.9 | – | – | – | 203 | 13.5 | 1487 | 11.3 | – | – | – | – | ||
| Oral cavity NOS | |||||||||||||||||
| Oropharynx | 120 | 23.8 | 881 | 25.0 | – | – | – | – | 428 | 28.4 | 3451 | 26.2 | – | – | – | – | |
| Hypopharynx | 15 | 3.0 | 173 | 4.9 | – | – | – | – | 103 | 6.8 | 1118 | 8.5 | – | – | – | – | |
| Oropharynx NOS | 82 | 16.2 | 392 | 11.1 | – | – | – | – | 167 | 11.1 | 1033 | 7.9 | – | – | – | – | |
| Overlapping palate | 12 | 2.4 | 54 | 1.5 | – | 1.5 | 163 | 1.2 | – | – | – | – | |||||
| Larynx | 61 | 12.1 | 506 | 14.4 | – | 16. | 4002 | 30.4 | – | – | – | – | |||||
| Overlapping OC, PH, LA | 0 | 0 0 | 9 | 0.3 | – | 81 | 16.0 | 362 | 10.3 | – | 0.7 | 61 | 0.5 | – | – | – | – |
| All head and neck | 505 | 100 | 3522 | 100 | – | 23 | 4.6 | 301 | 8.5 | – | 100 | 13 172 | 100 | – | – | – | – |
| p-Value (YA x older group)a | <0.001 | 111 | 21.0 | 844 | 23.9 | – | <0.001 | ||||||||||
| Tobacco smoking | |||||||||||||||||
| Never smoker | 231 | 45.7 | 1144 | 32.5 | 848 | 59.1 | 4003 | 64.2 | 251 | 16.8 | 1101 | 8.4 | 950 | 36.6 | 4698 | 28.5 | |
| Ever smoker | 274 | 57.3 | 2372 | 67.3 | 588 | 41.0 | 2229 | 35.8 | 1246 | 83.2 | 12 015 | 91.2 | 1644 | 63.4 | 11 785 | 71.5 | |
| p-Value (YA x older group) | <0.001 | <0.001 | <0.001 | <0.001 | |||||||||||||
| Alcohol drinking | |||||||||||||||||
| Never drinker | 208 | 41.2 | 1242 | 35.3 | 675 | 47.8 | 3010 | 48.3 | 171 | 11.4 | 911 | 6.9 | 533 | 20.6 | 2845 | 17.3 | |
| Ever drinker | 297 | 58.8 | 2263 | 64.2 | 736 | 52.2 | 3218 | 51.7 | 1326 | 88.6 | 12 188 | 92.5 | 2051 | 79.4 | 13 615 | 82.7 | |
| p-Value (YA x older group) | 0.013 | 0.761 | <0.001 | <0.001 | |||||||||||||
| Education level | |||||||||||||||||
| No education | 59 | 11.7 | 372 | 10.7 | 58 | 4.1 | 401 | 6.4 | 42 | 2.8 | 525 | 4.0 | 40 | 1.6 | 596 | 3.6 | |
| ≤Junior high school | 105 | 20.8 | 1078 | 30.9 | 407 | 28.9 | 2348 | 37.7 | 530 | 35.3 | 5852 | 44.4 | 822 | 31.9 | 6525 | 39.6 | |
| Some high school | 79 | 15.7 | 641 | 18.0 | 174 | 12.4 | 922 | 14.8 | 279 | 18.6 | 2250 | 17.1 | 417 | 16.2 | 2708 | 16.4 | |
| High school graduate | 85 | 16.9 | 535 | 15.1 | 203 | 14.4 | 781 | 12.6 | 222 | 14.8 | 1644 | 12.5 | 360 | 14.0 | 1807 | 11.0 | |
| Technical school / college | 98 | 19.4 | 620 | 17.4 | 304 | 21.6 | 1056 | 17.0 | 246 | 16.4 | 1699 | 12.9 | 534 | 20.7 | 2626 | 15.9 | |
| ≥College graduate | 78 | 15.5 | 275 | 7.9 | 263 | 18.7 | 714 | 11.5 | 181 | 12.1 | 1182 | 9.0 | 407 | 15.8 | 2208 | 13.4 | |
| p-Value (YA x older group)a | <0.001 | <0.001 | <0.001 | <0.001 | |||||||||||||
yo, years old; NOS, not otherwise specified; OC, oral cavity; PH, pharynx; LA, larynx.
aChi-squared test.