Table 6.
Diet and the risk of head and neck cancer according to sex and age subgroups. International Head and Neck Cancer Epidemiology Consortium
| Diet | Women ≤45 yo |
Women >45 yo |
Men ≤45 yo |
Men >45 yo |
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Case | Control | OR | (95% CI) | Case | Control | OR | (95% CI) | Case | Control | OR | (95% CI) | Case | Control | OR | (95% CI) | |
| Vegetablesa | ||||||||||||||||
| 1st quartile | 114 | 233 | 1.00 | 741 | 1012 | 1.00 | 403 | 601 | 1.00 | 3602 | 3550 | 1.00 | ||||
| 2nd quartile | 97 | 258 | 0.87 | (0.59, 1.27) | 624 | 1229 | 0.84 | (0.71, 0.99) | 294 | 514 | 0.86 | (0.68, 1.07) | 2407 | 3503 | 0.73 | (0.68, 0.80) |
| 3rd quartile | 85 | 65 | 0.84 | (0.57, 1.24) | 606 | 1344 | 0.81 | (0.69, 0.96) | 188 | 473 | 0.60 | (0.47, 0.76) | 2046 | 3255 | 0.70 | (0.64, 0.76) |
| 4th quartile | 78 | 303 | 0.67 | (0.45, 0.99) | 579 | 1565 | 0.72 | (0.61, 0.84) | 186 | 446 | 0.58 | (0.45, 0.74) | 1766 | 3753 | 0.59 | (0.54, 0.64) |
| p-trend | 0.052 | <0.001 | <0.001 | <0.001 | ||||||||||||
| Fruita | ||||||||||||||||
| 1st quartile | 156 | 292 | 1.00 | 834 | 919 | 1.00 | 471 | 640 | 1.00 | 3388 | 3821 | 1.00 | ||||
| 2nd quartile | 75 | 250 | 0.78 | (0.54, 1.14) | 553 | 1131 | 0.68 | (0.58, 0.81) | 237 | 516 | 0.67 | (0.53, 0.84) | 3482 | 2375 | 0.72 | (0.66, 0.78) |
| 3rd quartile | 69 | 21 | 0.72 | (0.49, 1.06) | 557 | 1501 | 0.64 | (0.54, 0.75) | 201 | 476 | 0.70 | (0.55, 0.88) | 3657 | 1956 | 0.65 | (0.60, 0.71) |
| 4th quartile | 49 | 235 | 0.58 | (0.38, 0.88) | 488 | 1481 | 0.55 | (0.47, 0.65) | 146 | 378 | 0.57 | (0.44, 0.74) | 3433 | 1571 | 0.56 | (0.51, 0.62) |
| p-trend | 0.008 | <0.001 | <0.001 | <0.001 | ||||||||||||
| Meata | ||||||||||||||||
| 1st quartile | 83 | 258 | 1.00 | 687 | 1248 | 1.00 | 246 | 25 | 1.00 | 2287 | 3326 | 1.00 | ||||
| 2nd quartile | 103 | 274 | 1.06 | (0.70, 1.60) | 647 | 1271 | 0.99 | (0.84, 1.17) | 221 | 484 | 0.76 | (0.58, 0.99) | 2221 | 3577 | 0.98 | (0.89, 1.07) |
| 3rd quartile | 91 | 251 | 1.12 | (0.74, 1.69) | 587 | 1301 | 1.00 | (0.85, 1.19) | 232 | 531 | 0.79 | (0.61, 1.03) | 2364 | 3615 | 1.04 | (0.95, 1.14) |
| 4th quartile | 88 | 249 | 1.12 | (0.73, 1.71) | 556 | 1157 | 1.05 | (0.88, 1.24) | 338 | 568 | 0.98 | (0.76, 1.25) | 2632 | 3277 | 1.17 | (1.07, 1.28) |
| p-trend | 0.556 | 0.609 | 0.857 | <0.001 | ||||||||||||
| Cerealsa | ||||||||||||||||
| 1st quartile | 99 | 303 | 1.00 | 683 | 1521 | 1.00 | 219 | 547 | 1.00 | 1997 | 2902 | 1.00 | ||||
| 2nd quartile | 86 | 227 | 0.95 | (0.62, 1.46) | 513 | 1079 | 0.93 | (0.78, 1.12) | 180 | 365 | 1.03 | (0.77, 1.38) | 1591 | 2469 | 0.82 | (0.73, 0.91) |
| 3rd quartile | 51 | 189 | 0.88 | (0.55, 1.42) | 465 | 948 | 1.21 | (1.00, 1.45) | 215 | 361 | 1.12 | (0.84, 1.51) | 1684 | 2778 | 0.91 | (0.82, 1.02) |
| 4th quartile | 69 | 181 | 1.38 | (0.88, 2.18) | 400 | 736 | 1.37 | (1.12, 1.67) | 223 | 421 | 0.97 | (0.72, 1.30) | 1895 | 2766 | 0.98 | (0.88, 1.10) |
| p-trend | 0.261 | <0.001 | 0.956 | 0.602 | ||||||||||||
aORs adjusted by sex, race, age, education level, pack-year of cigarette smoking and drink/day of alcohol (study centre as random intercept).