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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Hum Genet. 2015 Jan 14;134(3):343–358. doi: 10.1007/s00439-014-1524-3

Table 4.

BMI GWAS SNPs for BMI Differentially Expressed Genes linking by eQTLs

Gene -- Trait SNP -- Gene SNP -- Trait
Gene Chr.
for
gene
eQTL SNP Location
*hgeneExp2
Signature
P value
Signature
FDR
Phenotypic
Proportion
(Gene for Trait)
eSNP
p value
Cis
Trans
Phenotypic
Proportion
(SNP for Gene)
GWAS -
p value
Phenotypic Proportion
(SNP for Trait)
ETV5 chr3 rs9816226 Intronic (DGKG) 0.01 0.0002 0.001 0.003 4.44E-16 cis 0.012 7.61E-14 1.5E-4
AAGAB chr15 rs2278076 3' downstream
(MAP2K5)
0.04 0.0003 0.002 0.001 6.08E-06 cis 0.004 1.46E-10 0
CLN6 chr15 rs3784707 Intronic
(MAP2K5)
0.17 1.35E-10 2.58E-09 0.008 9.66E-06 cis 0.004 1.46E-10 0
SULT1A1 chr16 rs7498665 Coding (SH2B1) 0.21 0.01 0.05 0.001 5.54E-07 cis 0.006 1.75E-10 8.6E-5
SPNS1 0.05 8.25E-05 5.57E-04 0.004 5.77E-15 cis 0.012
TUFM 0.19 0.007 0.03 0.002 5.16E-08 cis 0.148
PTPRJ chr11 rs2290851 Intronic (FNBP4) 0.19 1.28E-17 5.79E-16 0.014 3.88E-07 cis 0.005 2.77E-10 4.5E-4
MTCH2 0.08 1.13E-05 9.26E-05 0.003 3.60E-14 cis 0.011
LIN7C chr11 rs1519480 3' downstream
(BDNF)
0.08 2.55E-06 2.39E-05 0.004 2.22E-14 cis 0.012 2.12E-09 4.4E-4

GWAS-p value: for BMI, the p values are from GIANT (Speliotes et al. 2010);