Figure 3. In vivo and in vitro measurements of the fluorescence intensity of TRH-labelled PSi particles.

(a) The fluorescence intensity of particles intratumorally injected in comparison with the intensity measured in vitro in the presence of ROS (R²=0.796) and (b) in vitro without ROS (R²=0.076). (c) The fluorescence intensity of particles injected into the healthy mammary fat pad in comparison with the intensity measured in vitro without ROS (R²=0.860). Data are the average percentage±s.d of two independent experiments, each including 15 SCID female mice (10 mice were induced with breast cancer and 5 served as a healthy control).