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Sections of the nodose ganglion collected 60 days after intraperitoneal capsaicin treatment revealed significant numbers of bromodeoxyuridine-labeled (DNA synthesis marker) nuclei located in PGP 9.5-immunoreactive (neuronal marker) perikarya. This population of dual labelled cells indicates that after capsaicin-induced cell death, ganglionic progenitors entered the cell cycle, proceeded to divide and differentiated to become sensory neurons.
