Fig 4. Additive effects of mTOR activation and AKT stimulation on follicle growth.
A) Graft weight increases. Ovaries from day 10 mice were incubated with IVA drugs with or without MHY1485. Ovaries were then grafted into hosts treated daily with FSH for 5 days before determination of graft weights. * P<0.05. B) Ovarian histology; bars: 100 um. C) Follicle dynamics. PO: preovulatory. N = 5. * P<0.05.