Table 2.

Right-heart catheterization and POPH treatment data on 100 waitlist candidates with approved POPH exceptions with hemodynamics consistent with POPH¹

Variable	Median (IQR)**
Pretreatment hemodynamics at time of MELD exception
PVR, Wood units	5.6 (4.6–5.6)
mPAP, mmHg	47 (41–55)
PCWP, mmHg	7 (5–15); (n=23)
TPG, mmHg	32 (26–36); (n=28)
Posttreatment values
PVR, Wood units; n=93	2.4 (1.7–3.2); (n=93)
mPAP, mmHg; n=97	30 (26–34); (n=97)
Response to treatment
Posttreatment decrease	−3.2 (−1.9, −4.4); (n=93)
in PVR, Wood units
Posttreatment decrease	−17 (−11, −24); (n=97)
in mPAP, mmHg
Meet posttreatment OPTN/UNOS guidelines †
Proportion with PVR	89 (95.7)
<5 Wood units, n (%)
Proportion with mPAP	76 (78.4)
< 35 mmHg, n (%)

IQR, interquartile range; MELD, Model for End-Stage Liver Disease; OPTN, Organ Procurement and Transplantation Network; POPH, portopulmonary hypertension; PVR, pulmonary vascular resistance; mPAP, mean pulmonary arterial pressure; PCWP, pulmonary capillary wedge pressure; TPG, trans-pulmonary gradient; UNOS, United Network for Organ Sharing.

^**Unless otherwise noted.

^†Reference (9).

¹Hemodynamic criteria consistent with POPH include an mPAP >25mmHg and PVR>3 Wood units prior to initiation of vasodilator therapy.