Table 3.

Multistate Cox regression model comparing the risk of death of POPH MELD exception point recipients to non-POPH, nonexception waitlist candidates from the time of listing/receiving exception points

Variable	Multivariable HR	p-Value1
Nonexception waitlist  candidates, n=34 180	1
POPH MELD exceptions  with hemodynamic criteria  consistent with POPH,  n=100 †	2.46 (1.73–3.52)	<0.001
POPH MELD exceptions  without hemodynamic  criteria consistent with  POPH, n=55 †	1.60 (1.04–2.47)	0.03
Male gender	0.91 (0.85–0.98)	0.01
Race/ethnicity		<0.001
White	1
Black	1.00 (0.90–1.10)
Hispanic	0.93 (0.85–1.03)
Asian	0.94 (0.82–1.08)
Other	0.89 (0.74–1.07)
Age at listing	1.36 (1.32–1.39)	<0.001
Primary diagnosis		<0.001
Hepatitis C	1
Alcohol	0.74 (0.70–0.78)
Hepatitis B	0.66 (0.57–0.76)
NASH/cryptogenic	0.79 (0.75–0.84)
Cholestatic	0.74 (0.69–0.80)
Autoimmune	0.83 (0.72–0.94)
Other	0.97 (0.88–1.06)
Listing laboratory MELD score	1.09 (1.08–1.10)	<0.001
Blood type		<0.001
O	1
A	1.05 (0.99–1.12)
B	0.93 (0.84–1.02)
AB	0.83 (0.73–0.94)

HR, hazard ratio; MELD, Model for End-Stage Liver Disease; POPH, portopulmonary hypertension.

^†Reference (9).

¹Adjusted for age, sex, race/ethnicity, age at listing, primary diagnosis, listing laboratory MELD score and blood type.