Abstract
Mutations within the shibire locus of Drosophila melanogaster are non-complementing alleles which result in reversible paralysis at 29° but retention of normal locomotor behavior at 22°.
Electroretinograms of six of the mutants have been recorded at various temperatures. Two changes occurred in the electroretinograms of flies carrying most of the alleles at high temperature: they lost the “on”- and “off”- transients of the normal electroretinogram, and the fast decay of the receptor potential was attenuated. For flies with four of the alleles, a base-line oscillation was also observed.
Analysis of electroretinograms of mosaic shibire flies indicates that the loss of the transients can be attributed to both a pre-synaptic and a post-synaptic effect.
Keywords: Diptera, vision, gynandromorphs, shibiret3, receptor potential
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Selected References
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