TABLE 2.
Plasma cytokines concentration in HFD-fed mice
| Control | ASO | |
| INFγ (pg/ml) | 0.28 ± 0.05 | 0.35 ± 0.07 |
| IL-1β (pg/ml) | 1.15 ± 0.10 | 1.19 ± 0.07 |
| IL-10 (pg/ml) | 10.7 ± 1.06 | 37.0 ± 8.46b |
| IL-12p70 (pg/ml) | 16.6 ± 0.58 | 16.2 ± 0.76 |
| IL-2 (pg/ml) | 0.48 ± 0.09 | 1.19 ± 0.19b |
| IL-4 (pg/ml) | 1.76 ± 0.07 | 1.72 ± 0.08 |
| IL-5 (pg/ml) | 2.82 ± 0.24 | 3.28 ± 0.25 |
| IL-6 (pg/ml) | 32.7 ± 6.27 | 149.8 ± 44.7a |
| KC/GRO (pg/ml) | 142.5 ± 13.9 | 217.7 ± 22.8a |
| TNF-α (pg/ml) | 11.5 ± 1.10 | 20.1 ± 1.47c |
Control and ApoA5 ASO treated mice fed a HFD for 8 weeks. Data are expressed as mean values ± SEM.
a
P < 0.05.
b
P < 0.01.
c
P < 0.001 by unpaired t-test compared with control mice.