Fig. 4.

Skin cholesterol accumulation and inflammation. A: Cholesterol level in skin tissue extracts of LDLR^−/−/apoAI^−/− recipient mice 16 weeks after HPC transplant and palm oil diet (control recipients: 10 females and 8 males; apoAI recipients: 7 females and 6 males). Representative proximal aorta of skin from healthy LDLR^−/− (left panel), control recipient LDLR^−/−/apoAI^−/− (middle panel), and apoAI recipient LDLR^−/−/apoAI^−/− (right panel) mice of H-and-E-stained sections (B), ORO-stained sections (C), and CD4-immuno­stained (red) on top of DAPI-stained (blue) sections (D). ** P < 0.01.