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. 2015 Mar;56(3):682–691. doi: 10.1194/jlr.P055491

Fig. 2.

Fig. 2.

ABCA1 expression and its function among study groups at baseline. A: ABCA1 protein expression was suppressed in macrophages from NCAD and CAD smokers compared with those from nonsmokers (each group, n = 6). B: Densitometry (p = 0.033, p < 0.001 vs. nonsmoker). C: ABCA1 mRNA was dramatically suppressed in CAD smokers but was upregulated in macrophages from NCAD smokers compared with that from nonsmokers (p < 0.001; each group, n = 10). D: ApoA-1-mediated cholesterol efflux was decreased in macrophages from CAD smokers (p < 0.001; n = 26) and NCAD smokers (p < 0.001; n = 24) compared with those from nonsmokers (n = 10) at baseline. ApoA-1-mediated cholesterol efflux was significantly lower from CAD smokers than from NCAD smokers (p = 0.017).