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. 2014 Oct 14;4:6620. doi: 10.1038/srep06620

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*Friedman test showing summarized effect for the all time points; comparisons between each time points showed Dunn's Multiple Comparison test: 0 wk vs 6 wk P < 0.05; 0 wk vs 12 wk P < 0.05; 0 wk vs 52 wk P < 0.05; 6 wk vs 12 wk P < 0.05; 6 wk vs 52 wk P < 0.05; 12 wk vs 52 wk P > 0.05.