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. 2015 Feb 18;11:385–394. doi: 10.2147/NDT.S61665

Table 3.

Questions for future research

• What additional comorbidities beyond anorexia and obsessive–compulsive disorder (OCD) are common in orthorexia and complicate treatment?
• How can existing orthorexia scales be modified to improve their psychometric properties? What additional measures should be used in conjunction with orthorexia scales for a comprehensive view of patient pathology?
• What cultural factors might explain the differences in prevalence rates across geographic regions?
• Are there meaningful subtypes of orthorexia, each with its unique set of external correlates?
• Are the cognitive weaknesses associated with orthorexia precursory, developmental risk factors or secondary sequelae?
• Which behavioral endophenotypes explain the greatest percentage of variance in orthorexic symptoms?
• What is the neuropathogenesis of orthorexia, and how can knowledge about the associated genetics, anatomy, chemistry, and physiology be applied to prevention and management practices?
• What is the effectiveness of various psychotherapy techniques for orthorexia? How can assessment be used to optimize treatment?