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. 2014 Nov 19;290(3):1522–1535. doi: 10.1074/jbc.M114.603902

TABLE 1.

Parameters for inhibition of BfAChE and EeAChE by Elec410 (italics) and Fab410 (plain)

BfAChEa,b EeAChE
IC50 Elec410 (nm) 10.9 ± 0.9 0.47 ± 0.18a,b
(8.1–13.7) (1.8–2.76)
IC50 Fab410 (nm) 33.4 ± 5.0 0.42 ± 0.03b,c
(11.8–54.9) (0.33–0.50)
Residual activity Elec410 (%) 28.1 ± 0.9 4.75 ± 0.55b,c
(25.2–31.0) (2.24–11.74)
Residual activity Fab410 (%) 13.7 ± 1.9 4.50 ± 0.62b,c
(5.4–22.1) (2.52–6.48)

a This study.

b Means ± S.E. from three (Fab410/BfAChE), four (IgG410/BfAChE and Fab410/EeAChE), and two (Elec410/EeAChE) independent experiments performed with duplicates. The 95% confidence intervals are provided in parentheses (p values <0.05).

c From Ref. 32 with modification.