FIGURE 3.

Phylogenetic analyses of PATs from Apicomplexa, free-living protists, yeast, and human. The phylogenetic tree reconstructed using MrBayes based on dCt region of all canonical PATs from apicomplexa, yeast, and human, and nonredundant representative set from free-living protists. The clusters with posterior probabilities greater than ∼0.6 are shown as clades, with posterior probabilities and bootstrap replicates indicated at the branching point. Clusters consisting only of apicomplexan members are shown in orange, and clusters consisting of sequences from both apicomplexan organisms and the free-living protists are shown in cyan. The yeast PATs that are orthologs of specific clusters are labeled in brown, and human orthologs are shown in blue. Features characteristic of a cluster are indicated alongside the cluster.