Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
CDK9 and CDK12 activity in the presence of DRB and FVP. Concentration series of (a) DRB and (b) FVP for CDK12/CycK and CDK9/CycT1 activity assayed using 1 μg of GST-yCTD (30 μm ATP, 37 °C, 30-min reaction time). Activity of each kinase is normalized to a value of one for 0 nm DRB or 0 nm FVP, respectively. Error bars are ± 1 S.E. of the mean, n = 3 (except for DRB 25 nm and 5000 nm where n = 1 and 2, respectively).
