Figure 1.

Intraperitoneal injection of voriconazole in mice selectively abolishes the ERG b-wave. (A) The average of normalized ERG recordings from three mice (six eyes) to flashes of −2.12 log (cd-s/m²) are displayed before (top traces) and after IP injection of 0.24 mg/g body weight voriconazole (red traces) or control (black traces). (B) The average of normalized ERG recordings from three mice (six eyes) to flashes of 2.27 log (cd-s/m²) are displayed before (top traces) and after IP injection of 0.24 mg/g body weight voriconazole (red traces) and control (black traces). (C) Changes in the b-wave peak amplitude normalized to their pre-injection amplitude over time following voriconazole injections of 0.06 mg/g and 0.24 mg/g, at a light intensity of 2.27 log (cd-s/m²).