TABLE 3.
n cases/controls | Model | Tertile 1 | Tertile 2 | Tertile 3 | P trend$ | |
---|---|---|---|---|---|---|
MDS * | ||||||
610/1891 | 0 | 1.00 (ref) | 1.05 (0.84;1.32) | 1.22 (0.94;1.58) | 0.12 | |
610/1891 | 1 | 1.00 (ref) | 1.03 (0.82;1.30) | 1.20 (0.92; 1.56) | 0.15 | |
387/1430 | 2 | 1.00 (ref) | 0.91 (0.70;1.18) | 1.05 (0.77;1.43) | 0.68 | |
387/1430 | 1adj | 1.00 (ref) | 0.91 (0.70;1.19) | 1.06 (0.78;1.45) | 0.62 | |
Postmenopausal | 409/1360 | 1 | 1.00 (ref) | 0.90 (0.68; 1.19) | 1.10 (0.80; 1.51) | 0.46 |
≥2 year after diagnosis | 518/1887 | 1 | 1.00 (ref) | 1.08 (0.85;1.38) | 1.22 (0.92;1.62) | 0.16 |
MDS no alcohol ** | ||||||
610/1891 | 0 | 1.00 (ref) | 1.02 (0.79; 1.32) | 1.18 (0.85; 1.63) | 0.32 | |
610/1891 | 1# | 1.00 (ref) | 0.99 (0.76; 1.29) | 1.15 (0.83; 1.60) | 0.40 | |
387/1430 | 2# | 1.00 (ref) | 0.99 (0.73; 1.35) | 1.02 (0.69; 1.52) | 0.92 | |
387/1430 | 1adj | 1.00 (ref) | 1.00 (0.74; 1.36) | 1.04 (0.70; 1.53) | 0.86 | |
Postmenopausal | 409/1360 | 1# | 1.00 (ref) | 0.95 (0.68; 1.32) | 1.14 (0.76; 1.71) | 0.57 |
≥2 year after diagnosis | 518/1887 | 1# | 1.00 (ref) | 0.93 (0.70;1.23) | 1.12 (0.79;1.59) | 0.52 |
P interaction MDS score with study centre 0.16;
p interaction MDS score without alcohol with study centre 0.22
P for trend was based on median tertile score
Model 0: unadjusted
Model 1: adjusted for exact age, parity, use of HRT, weight, height, physical activity, and menopausal status
Model 2: adjusted for exact age, parity, use of HRT, weight, height, physical activity, menopausal status, family history of breast cancer, breast feeding, and education level
Model 1adj: see model 1 but now including a reduced number of cases and controls as in model 2
This model was also adjusted for alcohol