TABLE 3.

Odds ratios for breast cancer risk according to tertiles of Mediterranean Diet Score (MDS), with and without including alcohol in MDS score

	n cases/controls	Model	Tertile 1	Tertile 2	Tertile 3	P trend$
MDS *
	610/1891	0	1.00 (ref)	1.05 (0.84;1.32)	1.22 (0.94;1.58)	0.12
	610/1891	1	1.00 (ref)	1.03 (0.82;1.30)	1.20 (0.92; 1.56)	0.15
	387/1430	2	1.00 (ref)	0.91 (0.70;1.18)	1.05 (0.77;1.43)	0.68
	387/1430	1adj	1.00 (ref)	0.91 (0.70;1.19)	1.06 (0.78;1.45)	0.62
Postmenopausal	409/1360	1	1.00 (ref)	0.90 (0.68; 1.19)	1.10 (0.80; 1.51)	0.46
≥2 year after diagnosis	518/1887	1	1.00 (ref)	1.08 (0.85;1.38)	1.22 (0.92;1.62)	0.16
MDS no alcohol **
	610/1891	0	1.00 (ref)	1.02 (0.79; 1.32)	1.18 (0.85; 1.63)	0.32
	610/1891	1#	1.00 (ref)	0.99 (0.76; 1.29)	1.15 (0.83; 1.60)	0.40
	387/1430	2#	1.00 (ref)	0.99 (0.73; 1.35)	1.02 (0.69; 1.52)	0.92
	387/1430	1adj	1.00 (ref)	1.00 (0.74; 1.36)	1.04 (0.70; 1.53)	0.86
Postmenopausal	409/1360	1#	1.00 (ref)	0.95 (0.68; 1.32)	1.14 (0.76; 1.71)	0.57
≥2 year after diagnosis	518/1887	1#	1.00 (ref)	0.93 (0.70;1.23)	1.12 (0.79;1.59)	0.52

^*P interaction MDS score with study centre 0.16;

^**p interaction MDS score without alcohol with study centre 0.22

^$P for trend was based on median tertile score

Model 0: unadjusted

Model 1: adjusted for exact age, parity, use of HRT, weight, height, physical activity, and menopausal status

Model 2: adjusted for exact age, parity, use of HRT, weight, height, physical activity, menopausal status, family history of breast cancer, breast feeding, and education level

Model 1adj: see model 1 but now including a reduced number of cases and controls as in model 2

^#This model was also adjusted for alcohol