Table 1. Baseline characteristics of the study population.
| Nitrite (n=40) | Placebo (n=40) | |
|---|---|---|
| Age (yr) (Mean±SD) | 56.35±11.16 | 57.60±13.20 |
| Sex (M/F) | 36/4 | 31/9 |
| Diabetes mellitus | 3 (7.5%) | 3 (7.5%) |
| Body-mass index (kg/m2) (Mean±SD)a | 28.97±5.14 | 28.58±5.17 |
| Hypertension | 20 (50.0%) | 14 (35.0%) |
| Hypercholesterolaemia | 16 (40.0%) | 12 (30.0%) |
| Heart rate (BPM) (Mean±SD) | 72.68±18.62 | 77.35±21.31 |
| Systolic BP (mmHg) (Mean±SD) | 124.48±29.92 | 136.13±26.99 |
| Ischaemia time (min) (Mean±SD)b | 207.05±76.34 | 171.63±67.72 |
| Door to Balloon time (min) (Mean±SD) | 46.45±13.76 | 42.35±11.94 |
| Culprit Vessel | ||
| Left anterior descending | 9 (22.5%) | 12(30%) |
| Circumflex | 5 (12.5%) | 5 (12.5%) |
| Right coronary | 26 (65.0%) | 23 (57.5%) |
| TIMI flow before PCI | ||
| 0 | 30 (75.0%) | 31 (77.5%) |
| 1 | 6 (15.0%) | 3 (7.5%) |
| 2 | 2 (5.0%) | 5 (12.5%) |
| 3 | 2 (5.0%) | 1 (2.5%) |
| 0/1 | 36 (90.0%) | 34 (85.0%) |
| Syntax score (Mean±SD) | 13.41±5.50 | 13.58±6.20 |
| DES use | 33 (82.5%) | 30 (78.9%) |
| Treatment before PCI | ||
| Morphine | 26 (43.3%) | 34 (56.7%) |
| Treatment at time of PCI | ||
| Heparin | 40 (100%) | 40 (100%) |
| Aspirin | 40 (100%) | 40 (100%) |
| Clopidogrel/Prasugrel (No/No) | 35/5 | 37/3 |
| Glycoprotein IIb/IIIa inhibitor | 40 (100% | 40 (100%) |
Values shown as number (%) unless otherwise stated.
Abbreviations: PCI, percutaneous coronary intervention;
TIMI, Thrombolysis in myocardial infarction; DES drug-eluting stent.
a
The body-mass index is the weight in kilograms divided by the square of the height in meters.
b
Ischaemia time determined from symptom to balloon times for each patient.