Skip to main content
. Author manuscript; available in PMC: 2015 Feb 25.
Published in final edited form as: Lancet. 2014 Dec 18;385(9963):117–171. doi: 10.1016/S0140-6736(14)61682-2

Table 4. Counterfactual deaths and population attributable fractions for diarrhoea and lower respiratory infection pathogens for 1990 and 2013.

Children younger than age 5 years
All ages
1990
2013
1990
2013
Rate of change for deaths 1990-2013 (%)
Deaths (thousands) Population attributable fractions (%) Deaths (thousands) Population attributable fractions (%) Deaths (thousands) Population attributable fractions (%) Deaths (thousands) Population attributable fractions (%)
Diarrhoea

Adenovirus 63·0 (44·4 to 89·9) 3·9 (2·7 to 5·5) 18·3 (11·8 to 25·5) 3·5 (2·4 to 4·9) 81·3 (55·9 to 115·9) 3·2 (2·1 to 4·4) 31·8 (21·5 to 44·7) 2·5 (1·7 to 3·6) −61·2% (−67·8 to −52·5)
Aeromonas 12·3 (6·4 to 21·4) 0·8 (0·4 to 1·3) 5·5 (2·6 to 10·1) 1·1 (0·5 to 1·9) 28·0 (16·7 to 44·9) 1·1 (0·7 to 1·7) 13·0 (7·3 to 22·0) 1·0 (0·6 to 1·7) −53·6% (−66·1 to −37·8)
Amoebiasis 5·8 (2·6 to 10·0) 0·4 (0·2 to 0·6) 1·3 (0·6 to 2·3) 0·2 (0·1 to 0·5) 18·3 (8·9 to 30·6) 0·7 (0·3 to 1·2) 11·3 (5·0 to 19·7) 0·9 (0·4 to 1·6) −39·1% (−57 to −17·5)
Campylobacter enteritis 20.8 (11·0 to 31·9) 1·3 (0·7 to 2·0) 9·5 (3·7 to 15·7) 1·8 (0·7 to 3·0) 28·4 (16·4 to 42·8) 1·1 (0·6 to 1·6) 14·1 (6·9 to 22·4) 1·1 (0·5 to 1·8) −50·7% (−63·7 to −37·5)
Cholera 81·7 (39·1 to 117·0) 5·1 (2·5 to 7·2) 45·2 (23·4 to 67·6) 8·7 (4·5 to 12·7) 125·3 (61·1 to 173·4) 4·9 (2·4 to 6·7) 69·9 (37·7 to 97·0) 5·5 (3·0 to 7·7) −44·3% (−56·8 to −26·6)
Clostridium difficile 2·1 (2·0 to 2·3) 0·1 (0·1 to 0·1) 2·5 (2·4 to 2·7) 0·5 (0·4 to 0·6) 20·8 (19·9 to 21·9) 0·8 (0·7 to 0·9) 41·5 (39·1 to 43·9) 3·3 (3·0 to 3·6) 99·4% (84·3 to 114·3)
Cryptosporidiosis 92·4 (68·7 to 125·1) 5·8 (4·3 to 7·8) 35·2 (25·9 to 48·2) 6·8 (5·1 to 9·3) 98·8 (72·8 to 132·7) 3·8 (2·8 to 5·2) 41·9 (30·0 to 58·4) 3·3 (2·4 to 4·7) −57·8% (−64·8 to −49·6)
Enteropathogenic Escherichia coli infection 4·3 (1·3 to 7·8) 0·3 (0·1 to 0·5) 1·8 (0·7 to 3·4) 0·3 (0·1 to 0·7) 4·3 (1·3 to 7·8) 0·2 (0·1 to 0·3) 1·8 (0·7 to 3·4) 0·1 (0·1 to 0·3) −57·5% (−76·5 to −32)
Enterotoxigenic Escherichia coli infection 86·0 (61·3 to 114·1) 5·4 (3·8 to 7·2) 23·1 (17·0 to 30·4) 4·4 (3·4 to 5·9) 134·7 (97·5 to 178·2) 5·2 (3·8 to 6·8) 59·2 (44·2 to 77·7) 4·7 (3·5 to 6·1) −56·0% (−63·0 to −46·9)
Norovirus 7·3 (2·7 to 11·8) 0·5 (0·2 to 0·7) 1·8 (0·7 to 3·1) 0·3 (0·1 to 0·6) 7·3 (2·7 to 11·8) 0·3 (0·1 to 0·5) 1·8 (0·7 to 3·2) 0·1 (0·1 to 0·2) −75·8% (−85·1 to −61·6)
Other Salmonella infections 19·2 (11·1 to 29·1) 1·2 (0·7 to 1·8) 3·8 (1·6 to 6·7) 0·7 (0·3 to 1·2) 58·9 (42·4 to 77·8) 2·3 (1·6 to 3·0) 24·3 (16·0 to 33·3) 1·9 (1·3 to 2·6) −58·9% (−65·4 to −51·1)
Rotaviral enteritis 398·9 (334·5 to 464·2) 24·8 (21·4 to 28·2) 122·4 (96·6 to 152·1) 23·5 (20·1 to 27·2) 477·5 (397·9 to 555·1) 18·5 (15·8 to 21·2) 176·6 (140·4 to 218·4) 14·0 (11·4 to 16·6) −63·2% (−68·5 to −57·1)
Shigellosis 161·0 (130·0 to 200·3) 10·0 (8·2 to 12·2) 33·4 (24·9 to 43·5) 6·4 (5·1 to 7·9) 254·2 (207·9 to 311·7) 9·9 (8·2 to 11·9) 73·9 (58·9 to 93·8) 5·8 (4·7 to 7·3) −70·9% (−74·4 to −67·3)
No identified aetiology* 652·4 (542·4 to 783·1) 40·6 (35·3 to 46·8) 215·9 (169·6 to 265·2) 41·5 (35·7 to 48·1) 1240·9 (1096·8 to 1421·5) 48·1 (43·5 to 53·5) 702·9 (619·2 to 796) 55·6 (51·4 to 60·3) −43·2% (−49·3 to −36·1)

Lower respiratory infections

Haemophilus influenzae type B pneumonia 427·1 (−39·8 to 853·4) 19·7 (−1·8 to 39·1) 108·7 (−9·9 to 226·9) 12·0 (−1·1 to 25·5) 427·1 (−39·8 to 853·4) 12·5 (−1·2 to 24·8) 108·7 (−9·9 to 226·9) 4·1 (−0·4 to 8·8) −75·1% (−79·1 to ·71−2)
Influenza 36·3 (14·2 to 73·5) 1·7 (0·7 to 3·3) 15·1 (5·7 to 30·4) 1·7 (0·6 to 3·3) 85·1 (36·1 to 156·2) 2·5 (1·1 to 4·5) 105·4 (45·3 to 188·1) 4·0 (1·7 to 7·3) 24·0% (3·4 to 47·7)
Pneumococcal pneumonia 652·4 (402·6 to 879·4) 30·1 (19·0 to 40·2) 264·0 (155·7 to 365·8) 29·2 (18·0 to 39·2) 919·5 (553·1 to 1320·5) 26·9 (16·3 to 38·4) 594·4 (295·6 to 970·2) 22·4 (11·4 to 35·9) −36·1% (−52·7 to −19·8)
Respiratory syncytial virus pneumonia 145·1 (82·7 to 228·0) 6·7 (3·8 to 10·5) 41·1 (23·0 to 65·5) 4·5 (2·6 to 7·1) 185·5 (114·4 to 268·6) 5·4 (3·5 to 7·9) 81·5 (53·6 to 109·9) 3·1 (2·0 to 4·2) −55·7% (−63 to −47·2)
No identified aetiology* 907·2 (407·3 to 1451·3) 41·9 (19·0 to 66·7) 476·2 (313·3 to 651·6) 52·6 (35·2 to 70·2) 1803·4 (1211·8 to 2452·5) 52·7 (35·4 to 71·1) 1762·6 (1385·3 to 2134·1) 66·5 (52·8 to 79·9) −0·8% (−19·8 to 22·9)

Data in parentheses are 95% uncertainty intervals.

*

Number or proportion of diarrhea or lower respiratory infection deaths attributable to any diarrhea or lower respiratory infection pathogens. Because of interaction between pathogens (especially for lower respiratory infection), the value is the minimum amount of unexplained deaths.