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. 2015 Feb 13;12:28. doi: 10.1186/s12974-015-0253-4

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© Perera et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Bio-plex analysis of cytokine expression profile in the nervous tissue and serum at 10 days post-CCI. Heat maps illustrating the summary of fold change expression of cytokines in the (A) LSN, (B) left DRG, (C) spinal cord, and (D) serum of immunized nerve-injured rats compared to control uninjured naïve rats at 10 days post-CCI. Yellow asterisks indicate significant differences in cytokine concentrations in treatment groups as compared to the uninjured control group (n ≥ 4 per group; one-way ANOVA with Dunnet’s multiple comparison test compared to the uninjured group).