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. Author manuscript; available in PMC: 2015 Feb 25.
Published in final edited form as: Vaccine. 2009 Jun 28;27(37):5120–5132. doi: 10.1016/j.vaccine.2009.06.037

Table 2. Binding analysis of sera and virus capture competition assay.

The sera at Week 30 from rabbits immunized with KNH1144 immunogens were analyzed. The result represents the reciprocal of the dilution that inhibits mAb-mediated virus by 50%. The serum titers are color-coded as in Table 1. Titers for self-competition Ab represent the concentration which inhibits mAb-mediated virus by 50%. The Ab titers are color-coded as follows: white boxes (titer > 10 μg/ml for mAbs or < 20 for sera), yellow boxes (titer = 0.11-10 μg/ml for mAbs or 20-1000 for sera), and red boxes (titer ≤ 0.1 μg/ml for mAbs and > 1000 for sera).

Serum Immunogen Virus capture competition
15e (CD4bs) E51/sCD4 (CD4i) 7B2 (cluster I)
5-1 KNH1144 gp120 <20 <20 <20
6-4 KNH1144 SOSIP 180 <20 <20
self-competition (μg/ml) 0.14 0.011 0.037