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. Author manuscript; available in PMC: 2016 Feb 15.
Published in final edited form as: Dev Biol. 2014 Dec 3;398(2):206–217. doi: 10.1016/j.ydbio.2014.11.021

Figure 6. Disrupting insulin/TOR signaling in the germline causes reduced growth, but does not induce P body aggregation.

Figure 6

(A–C) Control egg chambers with germline-specific Mat-GAL4 alone develop normally and exhibit large P body aggregates when females are starved. (D–F) The growth of egg chambers in females expressing InR shRNA in the germline is severely inhibited resulting in chains of similarly-sized egg chambers that finally degenerate. Enlarged P body aggregates do not form in fed or starved conditions. (G–I) Egg chambers expressing TOR shRNA in the germline have inhibited growth and do not form many enlarged P body aggregates in either fed or starved conditions. Egg chambers were stained with Me31B antibodies (A–G) or eIF4E antibodies (H, I). Scale bars are 20 μm.