Table 1.
Breast Milk Benefits
Probiotic | Bacteria sampled from maternal gut directly inoculate infant gut |
Prebiotic | Indigestible oligosaccharides |
Innate immunity | Antimicrobial peptides, lactoferrin and lysozyme |
Soluble CD14 recognizes LPS | |
Soluble TLR2 | |
Adaptive immunity | Secretory IgA specific to pathogens encountered in maternal gut |
Glycan decoy cell adhesion molecules |
Maternal breast milk contains both innate and adaptive immune factors, which shape the infant microflora and protect against pathogenic infection. In addition, breast milk contains live bacteria translocated from the maternal gut and prebiotic oligosaccharides to encourage growth of commensals.