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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: J Immunol. 2015 Feb 2;194(5):2268–2279. doi: 10.4049/jimmunol.1401724

Figure 7. Host CD40 drives differentiation of effector cells.

Figure 7

Mice were treated as in Figure 5 and cells were collected on Day 5 post-immunization. (A) Representative plots of KLRG1 and CD127 expression on liver CD8+ T cells and (B) aggregate KLRG1 expression data from liver and spleen. Panel (B) compares WT CD8+ T cells in WT and CD40−/− hosts (Mann-Whitney test) and panel (C) compares WT and CD40−/− CD8+ T cells in WT hosts (Wilcoxon matched pairs test). (D) Representative plots of CD25 expression on splenic CD8+ T cells and (E) aggregate data from liver and spleen. (E) Representative plots of CD122 expression on liver CD8+ T cells and (F) aggregate data from liver and spleen.