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. 2015 Feb 25;10(2):e0118655. doi: 10.1371/journal.pone.0118655

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© 2015 Otsuki et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 7 — A: Photomicrographs of CD68-positive macrophages and pulmonary vascular lesions in a Sugen/hypoxia rat 3 weeks after initial treatment. B: Number of perivascular CD68-positive macrophages per vessel in control, hypoxia, and Sugen/hypoxia groups at 3 and 5 weeks was compared with a one-way analysis of variance followed by Tukey-Kramer multiple comparison test. Number of perivascular CD68-positive macrophages per vessel (C) and the percentage of macrophage-positive intima (D) at different time points were compared with a one-way analysis of variance followed by Tukey-Kramer multiple comparison test. Values are mean ± SD. E: Positive correlation between the number of perivascular macrophages per vessel in a lung section and the percentage of occlusive lesions in a lung section (Pearson product-moment correlation coefficients). F: Percentage of the number of perivascular macrophages per vessel in that of total perivascular inflammatory cells, including macrophages, CD3+ T cells, and mast cells, at different time points were compared with a one-way analysis of variance followed by Tukey-Kramer multiple comparison test.