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Kaplan-Meier survival plot of mice (n = 15 per group) that were passively immunized i.p. with rabbit antiserum against Mrp4N (circles) or normal rabbit serum (triangles) and then challenged 24 h later with M28 GAS via the i.p. route. Survival after 14 days was 67% in the Mrp4N group versus 26% in the control group: P = 0.046, log rank chi-square test on Kaplan-Meier survival data.
