TABLE 1.
Amino acid sequences of mutations
| Mutation or truncation | Domain | Amino acid sequence
|
|
|---|---|---|---|
| Wild type | Mutanta | ||
| Mutations | |||
| CL5 | I | DD | AA |
| CL11 | I | DRD | AAA |
| CL16 | I | DE | AA |
| CL23 | I | EEGE | AAGA |
| CL30 | I | EE | AA |
| CL34 | I | SLSS | ALAA |
| CL38 | I | YGT | AGA |
| CL41 | I | SD | AA |
| CL46 | I | SS | AA |
| CL49 | I | YSR | AAA |
| Y49A | I | ASR | |
| S50A | I | YAR | |
| R51A | I | YSA | |
| CL121 | III | KRDR | AADA |
| CL153 | IV | ETFSPD | AAFAPA |
| E153A | IV | ATFSPD | |
| T154A | IV | EAFSPD | |
| S156A | IV | ETFAPD | |
| D158A | IV | ETFSPA | |
| CL173 | IV | TD | AA |
| CL177 | IV | RTR | AAA |
| CL209 | V | RFWTR | AFWAA |
| R209A | V | AFWTR | |
| T212A | V | RFWAR | |
| R213A | V | RFWTA | |
| Truncations | |||
| 66t | VILFL | VILG* | |
| 149t | LFAAA | LFAG* | |
| 181t | RALGI | RALG* | |
| 204t | SANFF | SANG* | |
| 211t | RFWTR | RFWG* | |
| 216t | AILNA | AILG* | |
a
*, stop codon.