Table 1. List of observed discrepancies between the SNPtrace Panel and STR comparisons.
Cell line 1 | Cell Line 2 | Identity score (SNP) | Identity score (STR) | Observation | |
---|---|---|---|---|---|
1 | NCI-H2691 | NCI-H2803 | 1.00 | 1.00 | Cell lines are identical, not previously known |
2 | KM-12 | PMF-ko14 | 0.99 | 0.72 | Cell lines are identical, not previously known |
3 | COR-L47 | COR-L51 | 0.78 | 0.44 | Cell lines reported as synonymous (Sanger), but have unique profiles |
4 | HM7 | MT-3 | 1.00 | 0.69 | Identical by SNP, weak identity by STR. Discrepancy likely due to MSI affecting STRs |
5 | LS-180 | MT-3 | 1.00 | 0.60 | Identical by SNP, weak identity by STR. Discrepancy likely due to MSI affecting STRs |
6 | LS-174T | MT-3 | 1.00 | 0.63 | Identical by SNP, weak identity by STR. Discrepancy likely due to MSI affecting STRs |