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. 2014 Oct 30;135(3):816–823. doi: 10.1038/jid.2014.425

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Copyright © 2015 The Society for Investigative Dermatology, Inc

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/

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Comparing the prevalence of copy number variations (CNVs) across the entire chromosomes between adult and pediatric conventional melanoma. (a) The frequency of CNVs in 95 nonacral adult cutaneous melanomas using the single-nucleotide polymorphism (SNP) array data from the study by Hodis et al. (2012) and (b) the frequency of CNVs in 11 pediatric conventional melanomas in our study. The 7q34 locus harboring BRAF was a common region of gain, whereas 9p21 and 10q23.3, spanning CDKN2A and PTEN, were common regions of loss in both adult and pediatric melanomas.