Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Pharmacokinetic parameters of SN-38 and pharmacogenetic data of patients received 180 mg/m2 of PEP02
| Patient unique number | AUC0–∞
(hr-ng/mL) |
C
max
(ng /mL) |
t
1/2
(hr) |
UGT1A1*6 | UGT1A1*28 |
|---|---|---|---|---|---|
| 201 | 906 | 13.3 | 41.4 | W/W | W/W |
| 202 | 549 | 10.4 | 28.2 | W/W | W/W |
| 203 | 3,084 | 23.3 | 59.0 | V/W | V/W |
| 103 | 1,159 | 10.2 | 104 | ND | ND |
V variant; W wild type
ND not done
