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. 2015 Feb 25;6:49. doi: 10.3389/fimmu.2015.00049

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Copyright © 2015 Sharma, Khosla, David, Rastogi, Vyas, Singh, Bhardwaj, Sahney, Maiwall, Sarin and Trehanpati.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) CD4+CD25+CD127^low Tregs were analyzed using CD25 and CD127 markers on CD4+ gated population of T cells. Representative flow-cytometric dot plots and scatter plot showing the frequencies of CD4+CD25+CD127^low Tregs in all three groups. (B) Scatter plot shows increased expression of FoXP3 positive CD4+CD25+CD127^low Tregs in HBV-HCC than non-HBVHCC (P = 0.002).