Figure 1. Fundus appearance of the patients treated with IAC . A. A calcified tumor in the nasal part of the fundus with a prominent vessel. B. The response of treatment after one IAC with melphalan (3 months). C. Another patient with a tumor (group D). D. The complete response of the tumor with lessening of the vitreous seeds and resulted chorioretinal atrophy and severe choroidal atrophy. This patient had severe diffuse arteriolitis the week after IAC that lasted more than 1 month.