Generation of allocation sequence |
0 no double-blinding |
2 computer-generated random numbers |
Description of withdrawals and drop-outs |
1 not described |
1 numbers and reasons are described |
Allocation concealment |
0 numbers and reasons are not described |
3 central randomization |
Efficacy of randomization |
2 sealed envelopes or similar |
2 pre-treatment variables in tabular from |
1 not described or inadequate |
1 balance of pre-treatment variables |
Investigator blindness |
1 balance of pre-treatment variables mentioned but not in tabular form |
2 identical placebo tables or similar |
0 no information report |
1 inadequate or not described |
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