TABLE 1.
Effect of hyperthermic stress on virus production in explanted ganglia
| Treatment | Result after time of explant (h):
|
|||||
|---|---|---|---|---|---|---|
| 22
|
48
|
72
|
||||
| % Virus positive (no. positive/no. tested) | Mean viral titera | % Virus positive (no. positive/no. tested) | Mean viral titera | % Virus positive (no. positive/no. tested) | Mean viral titera | |
| Explant | 70 (7/10) | 16.5 | 100 (10/10) | 1.4 × 104 | 100 (10/10) | 5.5 × 105 |
| Hyperthermia | 60 (6/10) | 6.3 | 10 (1/10) | 0.2 | 0 (0/10) | 0 |
| Hyperthermia + explantb | 94 (17/18) | 88.3 | 100 (10/10) | 1.5 × 104 | 100 (10/10) | 2.3 × 105 |
a
Mean viral titers are the averages of the numbers of PFU recovered from each pair of ganglia.
b
Mice were subjected to hyperthermic stress, and 22 h later ganglia were explanted for an additional 22, 48, or 72 h.